Rethymno Prefecture borders the prefecture of Chania to the west and the prefecture of Heraklion to the east.

Its capital is the city of Rethymno, famous for its Venetian castle called the Fortetza which is one of the biggest castles in Crete. The city of Rethymno has a population of 41 687 inhabitants (2001 census). Rethymnon town is situated in the Northern part of the island, almost at the middle of Crete and at the western part of Rethymnon prefecture. The town still maintains its old aristocratic appearance, with  buildings dating from the 16th century, Byzantine and Hellenic-Roman remains, a small Venetian harbor and narrow streets.
         
Rethymnon does not have an airport but the city is served by the airports of Chania and Heraklion. Rethymnon port is connected all year long to mainland Greece through the port of Piraeus.  
         
Night life can range from extremely intense in the pubs and bars around the harbor and inside the old city, to the relaxing small bars right on the beach.
         
Other important towns and villages are Plakias, Spili, Agia Galini, Sitia and Mirambellos.
         
Retymno Prefecture has a population of  86 532 (2005 census) and an area 1 496 km².
         
Here you can find beautiful popular beaches like Rethymnon Beach, Platanes Beach, Missiria Beach, Perivolia Beach, Platanias Beach, Koumbes Beach, Gerani Beach, Episkopi Beach, Kavros Beach (beaches located North West of Rethymnon Prefecture, following the route from  East to West), Geropotamos Beach, Panormos Beach, Bali Beach (beaches located North East of Rethymnon Prefecture, following the route from West to East), Rodakino Beach, Korakas Beach, Souda Beach, Plakias Beach,  Damnoni Beach, Ammoudi Beach, Shinaria Beach, Drimiskianos Beach, Kerames Beach, Ligres Beach, Akoumia Beach, Triopetra Beach, Agios Pavlos Beach (beaches located South West of Rethymnon Prefecture, following the route from West to East), Agios Georgios Beach, Agia Galini Beach (beaches located South East of Rethymnon Prefecture, following the route from West to East)